HLA and congenital adrenal hyperplasia linkage confirmed.
نویسنده
چکیده
noradrenaline release.8.9 While clonidine and the opiates have similar effects on the locus coeruleus, clonidine appears to exert specific effects through non-opiate, alpha-2 adrenergic receptors. 6, These data suggested that the opiate-withdrawal syndrome is due to increased noradrenergic neuronal activity in areas such as the locus coeruleus which are regulated both by alpha-2 adrenergic and opiate receptors. Our preliminary results in man support a noradrenergic system mediation of opiate withdrawal and suggest that clonidine may be a more definitive treatment for opiate withdrawal than others now available.
منابع مشابه
Congenital adrenal hyperplasia--a clinical and genetic survey. Are we detecting male salt-losers?
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UNLABELLED The study was aimed to find out the prevalence of non-classical congenital adrenal hyperplasia (NC-CAH) due to 21-hydroxylase deficiency (21-OHdef) among Greek women with hirsutism and polycystic ovary syndrome (PCOS) and to compare the results of ACTH stimulated 17-hydroxyprogesterone 60 min (17-OHP60) values, with human leukocyte antigens (HLA) phenotypes, in any patient diagnosed ...
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ورودعنوان ژورنال:
- Lancet
دوره 1 8070 شماره
صفحات -
تاریخ انتشار 1978